Hubungan Usia, Hemoglobin, dan Indeks Massa Tubuh dengan Perubahan Ukuran Tumor pada Kemoterapi Neoadjuvant Kanker Serviks Stadium IB2 dan IIA2 di RSUP Dr. M. Djamil Padang

Nisa Ayu Farma; Syamel Muhammad; Asterina Asterina

doi:10.25077/jikesi.v2i1.300

Nisa Ayu Farma Universitas Andalas
Syamel Muhammad Bagian Obstetri dan Ginekologi Fakultas Kedokteran Universitas Andalas
Asterina Asterina Bagian Kimia Fakultas Kedokteran Universitas Andalas Padang

DOI: https://doi.org/10.25077/jikesi.v2i1.300

Keywords: age, haemoglobin, body mass index, neoadjuvant chemotherapy, cervical cancer

Abstract

Background. On stage IB2 and IIA2 of cervical cancer standard treatment such as neoadjuvant chemotherapy is required. The changes in tumor size of this therapy is influenced by several factors, among others are Age, Hb, and BMI.
Objective. To determine the relationship of Age, Hb, and BMI with changes in tumor size to neoadjuvant chemotherapy of servical cancer
Methods. This of research was analytical research with using a cohort retrospective design with a total sample of 35 patients. The research instrument used was a medical record then analyzed with a with a dependent sample t-test and simple regression linier correlation test.
Results. The result obtained a moderate negative power relationship between age and changes in tumor size (R= -0,412 ; P= 0,014), and there was no significant relationship between changes in tumor size with hemoglobin rate ( R= -0,107 ; P= 0,541), and BMI ( R= -0,117 ; P= 0,545).
Conclusion. There is a significant relationship between age and changes in tumor size, and there is no significant relationship between hemoglobin and body mass index with changes in tumor size.